NHS Warns Against Mixing Naproxen and Aspirin with Ibuprofen

The National Health Service (NHS) has issued a warning advising against the combination of two common nonsteroidal anti-inflammatory drugs (NSAIDs), naproxen and aspirin, with ibuprofen. Mixing these medications can increase the risk of serious side effects, including gastric bleeding and renal complications.

This guidance comes as many individuals frequently rely on over-the-counter painkillers for relief from everyday ailments such as headaches, back pain, and common colds. Among these medications, ibuprofen is notably popular in the United Kingdom, marketed under brand names such as Nurofen, Calprofen, and Ibuleve. As an NSAID, ibuprofen works by inhibiting hormones that cause inflammation and pain, making it effective for various conditions, from menstrual pain to symptoms of colds and flu.

While ibuprofen can be beneficial, the NHS emphasized the importance of understanding its proper use to avoid adverse reactions. The health service cautioned that “ibuprofen does not mix well with some medicines,” particularly other NSAIDs like naproxen and aspirin. Taking these medications together can significantly heighten the risk of complications.

Understanding the Risks of NSAID Combinations

Common side effects of ibuprofen include indigestion, headaches, dizziness, and skin rashes. More severe side effects, although less frequent, can manifest as stomach ulcers or internal bleeding, which may present symptoms such as abdominal pain or vomiting blood. An allergic reaction can also occur, indicated by swelling or difficulty in breathing, as well as potential kidney issues, identifiable by symptoms such as blood in urine or swelling in extremities.

The NHS warns that the likelihood of serious side effects increases with higher doses of ibuprofen or prolonged use. It is also crucial to be aware of other medications that may contain NSAIDs, including some cough and cold remedies available over the counter. The NHS advises checking labels for ingredients like aspirin and ibuprofen before combining them with other treatments.

To ensure safety, individuals are encouraged to consult their doctor if they are taking any of the following medications before starting ibuprofen: anticoagulants like warfarin, treatments for hypertension, corticosteroids such as betamethasone or prednisolone, certain antibiotics, and antidepressants. Additionally, combining ibuprofen with Ginkgo biloba supplements should be avoided, as it can increase bleeding risks.

Immediate Action Required for Severe Symptoms

The NHS urges individuals to seek immediate medical attention or contact emergency services if they experience concerning symptoms while taking ibuprofen. These symptoms include dark-colored stools or the presence of blood in vomit, which may indicate stomach bleeding, and signs of kidney complications such as swelling in the ankles or a decrease in urination.

As consumers increasingly rely on NSAIDs for pain relief, understanding the potential interactions and side effects is essential for safe usage. The NHS continues to provide guidance to help individuals manage their health effectively while minimizing risks associated with medication combinations.